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The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro

Telomerase is a reverse transcriptase that synthesizes telomeric DNA repeats at the ends of eukaryotic chromosomes. Although it is minimally composed of a conserved catalytic protein subunit (TERT) and an RNA component, additional accessory factors present in the holoenzyme play crucial roles in the...

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Autori principali: AIGNER, STEFAN, CECH, THOMAS R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2004 by RNA Society 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370601/
https://ncbi.nlm.nih.gov/pubmed/15208446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7400704
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