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dGTP-dependent processivity and possible template switching of euplotes telomerase.

We have measured the processivity of telomeric DNA extension by Euplotes aediculatus telomerase at various concentrations of the nucleotide substrates dGTP and dTTP. The maximum processivity (approximately 3 repeats) was observed at approximately 100 microM of each dNTP. Processivity decreased as th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hammond, P W, Cech, T R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC146957/
https://ncbi.nlm.nih.gov/pubmed/9278493
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