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Crystal structure of the highly divergent pseudouridine synthase TruD reveals a circular permutation of a conserved fold

The pseudouridine (Ψ) synthases Pus7p and TruD define a family of RNA-modifying enzymes with no sequence similarity to previously characterized Ψ synthases. The 2.2 Å resolution structure of Escherichia coli TruD reveals a U-shaped molecule with a catalytic domain that superimposes closely on that o...

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Detalhes bibliográficos
Main Authors: HOANG, CHARMAINE, FERRÉ-D’AMARÉ, ADRIAN R.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by RNA Society 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370594/
https://ncbi.nlm.nih.gov/pubmed/15208439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7240504
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