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Quantitation of free energy profiles in RNA–ligand interactions by nucleotide analog interference mapping

RNA interactions with protein and small molecule ligands serve a wide variety of biochemical functions in the cell. To best understand the specificity and affinity of these interactions, the free energy contribution made by individual function groups in the RNA must be determined. As an efficient me...

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Detalhes bibliográficos
Main Authors: COCHRANE, JESSE C., BATEY, ROBERT T., STROBEL, SCOTT A.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2003 by RNA Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370492/
https://ncbi.nlm.nih.gov/pubmed/13130142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5102803
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