Investigation of adenosine base ionization in the hairpin ribozyme by nucleotide analog interference mapping.

Tertiary structure in globular RNA folds can create local environments that lead to pKa perturbation of specific nucleotide functional groups. To assess the prevalence of functionally relevant adenosine-specific pKa perturbation in RNA structure, we have altered the nucleotide analog interference ma...

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Detalhes bibliográficos
Main Authors: Ryder, S P, Oyelere, A K, Padilla, J L, Klostermeier, D, Millar, D P, Strobel, S A
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370189/
https://ncbi.nlm.nih.gov/pubmed/11680850
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