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Defining the chemical groups essential for Tetrahymena group I intron function by nucleotide analog interference mapping

Improved atomic resolution biochemical methods are needed to identify the chemical groups within an RNA that are essential to its activity. As a step toward this goal, we report the use of 5′-O-(1-thio)inosine monophosphate (IMPαS) in a nucleotide analog interference mapping (NAIM) assay that makes...

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Detalhes bibliográficos
Main Authors: Strobel, Scott A., Shetty, Kanaka
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20295/
https://ncbi.nlm.nih.gov/pubmed/9096319
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