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Defining the chemical groups essential for Tetrahymena group I intron function by nucleotide analog interference mapping

Improved atomic resolution biochemical methods are needed to identify the chemical groups within an RNA that are essential to its activity. As a step toward this goal, we report the use of 5′-O-(1-thio)inosine monophosphate (IMPαS) in a nucleotide analog interference mapping (NAIM) assay that makes...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Strobel, Scott A., Shetty, Kanaka
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20295/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9096319/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.7.2903
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