Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): Deciphering the basis for nucleotide selection

We explored the specificity and nature of the nucleotide-binding pocket of the CCA-adding enzyme (tRNA nucleotidyltransferase) by using CTP and ATP analogs as substrates for a panel of class I and class II enzymes. Overall, class I and class II enzymes displayed remarkably similar substrate requirem...

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Hauptverfasser: CHO, HYUNDAE D., OYELERE, ADEGBOYEGA K., STROBEL, SCOTT A., WEINER, ALAN M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Copyright 2003 by RNA Society 2003
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370463/
https://ncbi.nlm.nih.gov/pubmed/12869708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2110903
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