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Structure of the U6 RNA intramolecular stem–loop harboring an S(P)-phosphorothioate modification

Phosphorothioate-substitution experiments are often used to elucidate functionally important metal ion-binding sites on RNA. All previous experiments with S(P)-phosphorothioate-substituted RNAs have been done in the absence of structural information for this particular diastereomer. Yeast U6 RNA con...

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Autores principales: REITER, NICHOLAS J., NIKSTAD, LAURA J., ALLMANN, ANNE M., JOHNSON, RANDAL J., BUTCHER, SAMUEL E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Copyright 2003 by RNA Society 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370419/
https://ncbi.nlm.nih.gov/pubmed/12702812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2199103
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