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A conserved family of Saccharomyces cerevisiae synthases effects dihydrouridine modification of tRNA.

Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, as well as in some archaea. In Saccharomyces cerevisiae every sequenced tRNA has at least one such modification, and all but one have two or more. We have used a biochemical genomics approach to identify the gene e...

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Main Authors: Xing, Feng, Martzen, Mark R, Phizicky, Eric M
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370258/
https://ncbi.nlm.nih.gov/pubmed/12003496
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