The mechanism and regulation of deadenylation: identification and characterization of Xenopus PARN.

In Xenopus oocytes, the deadenylation of a specific class of maternal mRNAs results in their translational repression. Here we report the purification, characterization, and molecular cloning of the Xenopus poly(A) ribonuclease (xPARN). xPARN copurifies with two polypeptides of 62 kDa and 74 kDa, an...

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Bibliographic Details
Main Authors: Copeland, P R, Wormington, M
Format: Artigo
Language:Inglês
Published: 2001
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370141/
https://ncbi.nlm.nih.gov/pubmed/11424938
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