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Nuclear Tau, p53 and Pin1 Regulate PARN-Mediated Deadenylation and Gene Expression
While nuclear tau plays a role in DNA damage response (DDR) and chromosome relaxation, the mechanisms behind these functions are not fully understood. Here, we show that tau forms complex(es) with factors involved in nuclear mRNA processing such as tumor suppressor p53 and poly(A)-specific ribonucle...
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| Yayımlandı: | Front Mol Neurosci |
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| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6843027/ https://ncbi.nlm.nih.gov/pubmed/31749682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00242 |
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