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mRNA deadenylation by PARN is essential for embryogenesis in higher plants

Deadenylation of mRNA is often the first and rate-limiting step in mRNA decay. PARN, a poly(A)-specific 3′ →5′ ribonuclease which is conserved in many eukaryotes, has been proposed to be primarily responsible for such a reaction, yet the importance of the PARN function at the whole-organism level ha...

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Bibliografiske detaljer
Main Authors: REVERDATTO, SERGEI V., DUTKO, JAMES A., CHEKANOVA, JULIA A., HAMILTON, DOUGLAS A., BELOSTOTSKY, DMITRY A.
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2004 by RNA Society 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370610/
https://ncbi.nlm.nih.gov/pubmed/15247430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7540204
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