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The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes.

Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. We previously described the purification of a poly(A)-specific 3'-...

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Autors principals: Körner, C G, Wormington, M, Muckenthaler, M, Schneider, S, Dehlin, E, Wahle, E
Format: Artigo
Idioma:Inglês
Publicat: 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170868/
https://ncbi.nlm.nih.gov/pubmed/9736620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.18.5427
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