Modulation of Adenovirus Vector Tropism via Incorporation of Polypeptide Ligands into the Fiber Protein

The efficacy of adenovirus (Ad)-based gene therapy might be significantly improved if viral vectors capable of tissue-specific gene delivery could be developed. Previous attempts to genetically modify the tropism of Ad vectors have been only partially successful, largely due to the limited repertoir...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Belousova, Natalya, Krendelchtchikova, Valentina, Curiel, David T., Krasnykh, Victor
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2002
Sujets:	Gene Therapy
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12163581/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.17.8621-8631.2002
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