Ectodomain of Coxsackievirus and Adenovirus Receptor Genetically Fused to Epidermal Growth Factor Mediates Adenovirus Targeting to Epidermal Growth Factor Receptor-Positive Cells

Human adenovirus (Ad) is extensively used for a variety of gene therapy applications. However, the utility of Ad vectors is limited due to the low efficiency of Ad-mediated gene transfer to target cells expressing marginal levels of the Ad fiber receptor. Therefore, the present generation of Ad vect...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Dmitriev, Igor, Kashentseva, Elena, Rogers, Buck E., Krasnykh, Victor, Curiel, David T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112205/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10888627/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.15.6875-6884.2000
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