The C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5' splice site.

Ítems similars

• The 100-kda U5 snRNP protein (hPrp28p) contacts the 5' splice site through its ATPase site.
  per: Ismaïli, N, et al.
  Publicat: (2001)
• Functional interactions of Prp8 with both splice sites at the spliceosomal catalytic center
  per: Siatecka, Miroslawa, et al.
  Publicat: (1999)
• The canonical GU dinucleotide at the 5' splice site is recognized by p220 of the U5 snRNP within the spliceosome.
  per: Reyes, J L, et al.
  Publicat: (1996)
• Elimination of mRNA splicing by a point mutation outside the conserved GU at 5' splice sites.
  per: Montell, C, et al.
  Publicat: (1984)
• Identification and functional analysis of hPRP17, the human homologue of the PRP17/CDC40 yeast gene involved in splicing and cell cycle control.
  per: Ben Yehuda, S, et al.
  Publicat: (1998)