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The C-terminal region of hPrp8 interacts with the conserved GU dinucleotide at the 5' splice site.

A U5 snRNP protein, hPrp8, forms a UV-induced crosslink with the 5' splice site (5'SS) RNA within splicing complex B assembled in trans- as well as in cis-splicing reactions. Both yeast and human Prp8 interact with the 5'SS, branch site, polypyrimidine tract, and 3'SS during spli...

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Detalhes bibliográficos
Main Authors: Reyes, J L, Gustafson, E H, Luo, H R, Moore, M J, Konarska, M M
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369749/
https://ncbi.nlm.nih.gov/pubmed/10024169
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