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Elimination of mRNA splicing by a point mutation outside the conserved GU at 5' splice sites.

Nearly all mRNA introns begin with the dinucleotide GU. Mutations in either of these virtually invariant bases have been found to inactivate the corresponding 5' splice site. Until now single base changes in neighboring bases have not been found to completely inactivate a 5' splice site. H...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Montell, C, Berk, A J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1984
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318792/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6587322/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.9.3821
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