Elimination of mRNA splicing by a point mutation outside the conserved GU at 5' splice sites.
Nearly all mRNA introns begin with the dinucleotide GU. Mutations in either of these virtually invariant bases have been found to inactivate the corresponding 5' splice site. Until now single base changes in neighboring bases have not been found to completely inactivate a 5' splice site. Here we sho...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1984
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6587322/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.9.3821 |
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