The adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase
Activation of the superoxide-producing phagocyte NADPH oxidase, crucial in host defense, requires the cytosolic proteins p67(phox) and p47(phox). They translocate to the membrane upon cell stimulation and activate flavocytochrome b(558), the membrane-integrated catalytic core of this enzyme system....
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| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2002
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12456638/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf642 |
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