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SIRPα Controls the Activity of the Phagocyte NADPH Oxidase by Restricting the Expression of gp91phox

The phagocyte NADPH oxidase mediates oxidative microbial killing in granulocytes and macrophages. However, because the reactive oxygen species produced by the NADPH oxidase can also be toxic to the host, it is essential to control its activity. Little is known about the endogenous mechanism(s) that...

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Bibliografiske detaljer
Principais autores: Ellen M. van Beek, Julian Alvarez Zarate, Robin van Bruggen, Karin Schornagel, Anton T.J. Tool, Takashi Matozaki, Georg Kraal, Dirk Roos, Timo K. van den Berg
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2012-10-01
Serier:Cell Reports
Online adgang:http://www.sciencedirect.com/science/article/pii/S2211124712002677
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