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The adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase
Activation of the superoxide-producing phagocyte NADPH oxidase, crucial in host defense, requires the cytosolic proteins p67(phox) and p47(phox). They translocate to the membrane upon cell stimulation and activate flavocytochrome b(558), the membrane-integrated catalytic core of this enzyme system....
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2002
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136946/ https://ncbi.nlm.nih.gov/pubmed/12456638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf642 |
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