Role of heparan sulfate domain organization in endostatin inhibition of endothelial cell function
The anti-angiogenic activity of endostatin (ES) depends on interactions with heparan sulfate (HS). In the present study, intact HS chains of ≥15 kDa bound quantitatively to ES whereas N-sulfated HS decasaccharides, with affinity for several fibroblast growth factor (FGF) species, failed to bind. Ins...
Zapisane w:
| Wydane w: | EMBO J |
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| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2002
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136942/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12456637/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf638 |
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