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The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling

Double-strand breaks (DSBs) elicit a DNA damage response, resulting in checkpoint-mediated cell-cycle delay and DNA repair. The Saccharomyces cerevisiae Sae2 protein is known to act together with the MRX complex in meiotic DSB processing, as well as in DNA damage response during the mitotic cell cyc...

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Autors principals: Clerici, Michela, Mantiero, Davide, Lucchini, Giovanna, Longhese, Maria Pia
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369247/
https://ncbi.nlm.nih.gov/pubmed/16374511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400593
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