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Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation

Given that ligand binding is essential for the rapid internalization of epidermal growth factor receptor (EGFR), the events induced by ligand binding probably contribute to the regulation of EGFR internalization. These events include receptor dimerization, activation of intrinsic tyrosine kinase act...

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Autori principali: Wang, Qian, Villeneuve, Greg, Wang, Zhixiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369181/
https://ncbi.nlm.nih.gov/pubmed/16113650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400491
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