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Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation
Given that ligand binding is essential for the rapid internalization of epidermal growth factor receptor (EGFR), the events induced by ligand binding probably contribute to the regulation of EGFR internalization. These events include receptor dimerization, activation of intrinsic tyrosine kinase act...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1369181/ https://ncbi.nlm.nih.gov/pubmed/16113650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400491 |
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