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Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation

Given that ligand binding is essential for the rapid internalization of epidermal growth factor receptor (EGFR), the events induced by ligand binding probably contribute to the regulation of EGFR internalization. These events include receptor dimerization, activation of intrinsic tyrosine kinase act...

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Detalhes bibliográficos
Main Authors: Wang, Qian, Villeneuve, Greg, Wang, Zhixiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369181/
https://ncbi.nlm.nih.gov/pubmed/16113650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400491
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