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Ablation of the spindle assembly checkpoint by a compound targeting Mps1
The spindle assembly checkpoint ensures accurate chromosome segregation by delaying anaphase initiation until all chromosomes are properly attached to the mitotic spindle. Here, we show that the previously reported c-Jun amino-terminal kinase (JNK) inhibitor SP600125 effectively disrupts spindle che...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1369161/ https://ncbi.nlm.nih.gov/pubmed/16113653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400483 |
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