Recruitment of the Histone Methyltransferase SUV39H1 and Its Role in the Oncogenic Properties of the Leukemia-Associated PML-Retinoic Acid Receptor Fusion Protein

Leukemia-associated fusion proteins establish aberrant transcriptional programs, which result in the block of hematopoietic differentiation, a prominent feature of the leukemic phenotype. The dissection of the mechanisms of deregulated transcription by leukemia fusion proteins is therefore critical...

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Bibliographic Details
Main Authors: Carbone, Roberta, Botrugno, Oronza A., Ronzoni, Simona, Insinga, Alessandra, Di Croce, Luciano, Pelicci, Pier Giuseppe, Minucci, Saverio
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367206/
https://ncbi.nlm.nih.gov/pubmed/16449642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.4.1288-1296.2006
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