An E2F Binding-Deficient Rb1 Protein Partially Rescues Developmental Defects Associated with Rb1 Nullizygosity

Rb1 is essential for normal embryonic development, as null mice die in midgestation with widespread unscheduled cell proliferation. Rb1 protein (pRb) mediates cell cycle control by binding E2F transcription factors and repressing expression from E2F-dependent promoters. An increasing amount of evide...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sun, Huifang, Chang, Yanjie, Schweers, Brett, Dyer, Michael A., Zhang, Xiaojing, Hayward, Simon W., Goodrich, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367194/
https://ncbi.nlm.nih.gov/pubmed/16449662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.4.1527-1537.2006
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados