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Scalable Generation of High-Titer Recombinant Adeno-Associated Virus Type 5 in Insect Cells
We established a method for production of recombinant adeno-associated virus type 5 (rAAV5) in insect cells by use of baculovirus expression vectors. One baculovirus harbors a transgene between the inverted terminal repeat sequences of type 5, and the second expresses Rep78 and Rep52. Interestingly,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1367135/ https://ncbi.nlm.nih.gov/pubmed/16439543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.1874-1885.2006 |
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