Three-Dimensional Visualization of FKBP12.6 Binding to an Open Conformation of Cardiac Ryanodine Receptor

The cardiac isoform of the ryanodine receptor (RyR2) from dog binds predominantly a 12.6-kDa isoform of the FK506-binding protein (FKBP12.6), whereas RyR2 from other species binds both FKBP12.6 and the closely related isoform FKBP12. The role played by FKBP12.6 in modulating calcium release by RyR2...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sharma, Manjuli Rani, Jeyakumar, Loice H., Fleischer, Sidney, Wagenknecht, Terence
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Biophysical Society 2006
Gaiak:
Channels, Receptors, and Electrical Signaling
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367015/
https://ncbi.nlm.nih.gov/pubmed/16214874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.063503
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