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The Conformation of Calsequestrin Determines Its Ability to Regulate Skeletal Ryanodine Receptors

Ca(2+) efflux from the sarcoplasmic reticulum decreases when store Ca(2+) concentration falls, particularly in skinned fibers and isolated vesicles where luminal Ca(2+) can be reduced to very low levels. However ryanodine receptor activity in many single channel studies is higher when the luminal fr...

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Detalhes bibliográficos
Main Authors: Wei, Lan, Varsányi, Magdolna, Dulhunty, Angela F., Beard, Nicole A.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1518631/
https://ncbi.nlm.nih.gov/pubmed/16698782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.082610
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