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Calsequestrin is an inhibitor of skeletal muscle ryanodine receptor calcium release channels.

We provide novel evidence that the sarcoplasmic reticulum calcium binding protein, calsequestrin, inhibits native ryanodine receptor calcium release channel activity. Calsequestrin dissociation from junctional face membrane was achieved by increasing luminal (trans) ionic strength from 250 to 500 mM...

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Bibliografiske detaljer
Main Authors: Beard, Nicole A, Sakowska, Magdalena M, Dulhunty, Angela F, Laver, Derek R
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302471/
https://ncbi.nlm.nih.gov/pubmed/11751318
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