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Effect of Protein Binding on Ultrafast DNA Dynamics: Characterization of a DNA:APE1 Complex
Synthetic oligonucleotides with a fluorescent coumarin group replacing a basepair have been used in recent time-resolved Stokes-shift experiments to measure DNA dynamics on the femtosecond to nanosecond timescales. Here, we show that the APE1 endonuclease cleaves such a modified oligonucleotide at t...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Biophysical Society
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366978/ https://ncbi.nlm.nih.gov/pubmed/16199493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.062695 |
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