A Mutant of Human Papillomavirus Type 16 E6 Deficient in Binding α-Helix Partners Displays Reduced Oncogenic Potential In Vivo

Human papillomaviruses (HPVs) are small DNA tumor viruses that are the causative agent of warts and are associated with many anogenital cancers. The viral gene encoding the E6 protein has been found to be involved in HPV oncogenesis. E6 is known to inactivate the cellular tumor suppressor, p53. In a...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Nguyen, Marie, Song, Shiyu, Liem, Amy, Androphy, Elliot, Liu, Yun, Lambert, Paul F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438630/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.24.13039-13048.2002
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