Immunological ignorance of an E7-encoded cytolytic T-lymphocyte epitope in transgenic mice expressing the E7 and E6 oncogenes of human papillomavirus type 16.

Certain human papillomaviruses (HPV) have been implicated in the etiology of cervical malignancies, and the E7 and E6 gene products of HPV type 16 are frequently expressed in these lesions. However, cytolytic T-lymphocyte (CTL)-mediated responses to HPV are rarely detectable in patients with cervica...

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Detalhes bibliográficos
Main Authors: Melero, I, Singhal, M C, McGowan, P, Haugen, H S, Blake, J, Hellstrom, K E, Yang, G, Clegg, C H, Chen, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC191552/
https://ncbi.nlm.nih.gov/pubmed/9094677
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