A Mutant of Human Papillomavirus Type 16 E6 Deficient in Binding α-Helix Partners Displays Reduced Oncogenic Potential In Vivo

Human papillomaviruses (HPVs) are small DNA tumor viruses that are the causative agent of warts and are associated with many anogenital cancers. The viral gene encoding the E6 protein has been found to be involved in HPV oncogenesis. E6 is known to inactivate the cellular tumor suppressor, p53. In a...

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Опубліковано в::	J Virol
Автори:	Nguyen, Marie, Song, Shiyu, Liem, Amy, Androphy, Elliot, Liu, Yun, Lambert, Paul F.
Формат:	Artigo
Мова:	Inglês
Опубліковано:	American Society for Microbiology (ASM) 2002
Предмети:	Virus-Cell Interactions
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438630/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.24.13039-13048.2002
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