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Homology Modeling Identifies C-Terminal Residues that Contribute to the Ca(2+) Sensitivity of a BK(Ca) Channel
Activation of BK(Ca) channels by direct Ca(2+) binding and membrane depolarization occur via independent and additive molecular processes. The “calcium bowl” domain is critically involved in Ca(2+)-dependent gating, and we have hypothesized that a sequence within this domain may resemble an EF hand...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Biophysical Society
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366805/ https://ncbi.nlm.nih.gov/pubmed/16100257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.063610 |
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