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Specific and Nonspecific Hybridization of Oligonucleotide Probes on Microarrays
Gene expression analysis by means of microarrays is based on the sequence-specific binding of RNA to DNA oligonucleotide probes and its measurement using fluorescent labels. The binding of RNA fragments involving sequences other than the intended target is problematic because it adds a chemical back...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Biophysical Society
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366534/ https://ncbi.nlm.nih.gov/pubmed/15834006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.055343 |
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