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"Hook"-calibration of GeneChip-microarrays: Chip characteristics and expression measures

BACKGROUND: Microarray experiments rely on several critical steps that may introduce biases and uncertainty in downstream analyses. These steps include mRNA sample extraction, amplification and labelling, hybridization, and scanning causing chip-specific systematic variations on the raw intensity le...

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Bibliographic Details
Main Authors: Binder, Hans, Krohn, Knut, Preibisch, Stephan
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543012/
https://ncbi.nlm.nih.gov/pubmed/18759984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-3-11
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