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Specific and Nonspecific Hybridization of Oligonucleotide Probes on Microarrays

Gene expression analysis by means of microarrays is based on the sequence-specific binding of RNA to DNA oligonucleotide probes and its measurement using fluorescent labels. The binding of RNA fragments involving sequences other than the intended target is problematic because it adds a chemical back...

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Bibliografski detalji
Glavni autori: Binder, Hans, Preibisch, Stephan
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366534/
https://ncbi.nlm.nih.gov/pubmed/15834006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.055343
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