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Specific and Nonspecific Hybridization of Oligonucleotide Probes on Microarrays

Gene expression analysis by means of microarrays is based on the sequence-specific binding of RNA to DNA oligonucleotide probes and its measurement using fluorescent labels. The binding of RNA fragments involving sequences other than the intended target is problematic because it adds a chemical back...

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Bibliografiska uppgifter
Huvudupphovsmän: Binder, Hans, Preibisch, Stephan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Biophysical Society 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366534/
https://ncbi.nlm.nih.gov/pubmed/15834006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.055343
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