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Transient Induction of Cyclin T1 during Human Macrophage Differentiation Regulates Human Immunodeficiency Virus Type 1 Tat Transactivation Function

The human immunodeficiency virus type 1 (HIV-1) Tat protein is essential for viral replication and stimulates transcription of the integrated provirus by recruiting the kinase complex TAK/P-TEFb, composed of cyclin T1 (CycT1) and Cdk9, to the viral TAR RNA element. TAK/P-TEFb phosphorylates the RNA...

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Bibliografische gegevens
Hoofdauteurs: Liou, Li-Ying, Herrmann, Christine H., Rice, Andrew P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136632/
https://ncbi.nlm.nih.gov/pubmed/12368300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.10579-10587.2002
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