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Transient Induction of Cyclin T1 during Human Macrophage Differentiation Regulates Human Immunodeficiency Virus Type 1 Tat Transactivation Function

The human immunodeficiency virus type 1 (HIV-1) Tat protein is essential for viral replication and stimulates transcription of the integrated provirus by recruiting the kinase complex TAK/P-TEFb, composed of cyclin T1 (CycT1) and Cdk9, to the viral TAR RNA element. TAK/P-TEFb phosphorylates the RNA...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Liou, Li-Ying, Herrmann, Christine H., Rice, Andrew P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136632/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368300/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.21.10579-10587.2002
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