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Sequence-specific interaction of Tat protein and Tat peptides with the transactivation-responsive sequence element of human immunodeficiency virus type 1 in vitro.

Bacterially expressed Tat protein of human immunodeficiency virus type 1 binds selectively to short RNA transcripts containing the viral transactivation-responsive element (TAR). Sequences sufficient for Tat interaction map to the distal portion of the TAR stem-loop. We show that critical sequences...

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Autores principales: Cordingley, M G, LaFemina, R L, Callahan, P L, Condra, J H, Sardana, V V, Graham, D J, Nguyen, T M, LeGrow, K, Gotlib, L, Schlabach, A J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC55085/
https://ncbi.nlm.nih.gov/pubmed/2247474
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