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Identification of the Hepatitis C Virus E2 Glycoprotein Binding Site on the Large Extracellular Loop of CD81
The binding of hepatitis C virus glycoprotein E2 to the large extracellular loop (LEL) of CD81 has been shown to modulate human T-cell and NK cell activity in vitro. Using random mutagenesis of a chimera of maltose-binding protein and LEL residues 113 to 201, we have determined that the E2-binding s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2002
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136624/ https://ncbi.nlm.nih.gov/pubmed/12368358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.11143-11147.2002 |
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