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Expression and Characterization of a Minimal Hepatitis C Virus Glycoprotein E2 Core Domain That Retains CD81 Binding

The hepatitis C virus glycoprotein E2 receptor-binding domain is encompassed by amino acids 384 to 661 (E2(661)) and contains two hypervariable sequences, HVR1 and HVR2. E2 sequence comparisons revealed a third variable region, located between residues 570 and 580, that varies widely between genotyp...

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Détails bibliographiques
Auteurs principaux: McCaffrey, Kathleen, Boo, Irene, Poumbourios, Pantelis, Drummer, Heidi E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951388/
https://ncbi.nlm.nih.gov/pubmed/17581991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02782-06
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