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Evolutionary Dynamics of Viral Attenuation

The genetic trajectory leading to viral attenuation was studied in a canine parvovirus (CPV) strain grown on dog kidney cells for 115 transfers. Consensus sequences of viral populations at passages 0, 3, 30, 50, 80, and 115 were obtained from PCR products covering 86% of the genome; clones from each...

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Bibliografische gegevens
Hoofdauteurs: Badgett, Marty R., Auer, Alexandra, Carmichael, Leland E., Parrish, Colin R., Bull, James J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136581/
https://ncbi.nlm.nih.gov/pubmed/12239331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.20.10524-10529.2002
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