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Evolutionary Dynamics of Viral Attenuation
The genetic trajectory leading to viral attenuation was studied in a canine parvovirus (CPV) strain grown on dog kidney cells for 115 transfers. Consensus sequences of viral populations at passages 0, 3, 30, 50, 80, and 115 were obtained from PCR products covering 86% of the genome; clones from each...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136581/ https://ncbi.nlm.nih.gov/pubmed/12239331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.20.10524-10529.2002 |
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