Pharmacokinetic and pharmacodynamic analysis of a novel leukotriene biosynthesis inhibitor, MK-0591, in healthy volunteers.

1. The pharmacokinetic and pharmacodynamic properties of a novel 2-indolealkanoic acid derivative (MK-0591), a potent inhibitor of leukotriene biosynthesis, were investigated in healthy male Japanese volunteers. Single oral doses of 50, 125, 250 and 500 mg and multiple oral doses of 125 mg twice dai...

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Hlavní autoři: Uematsu, T, Kanamaru, M, Kosuge, K, Hara, K, Uchiyama, N, Takenaga, N, Tanaka, W, Friedman, B S, Nakashima, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1365028/
https://ncbi.nlm.nih.gov/pubmed/8527269
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